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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb3853116a29f0869d27ef93944fa30a98e865c2cdf0d83efdcdabf3c02f7fc4' 
  AND token = 'd5I5/qKKSUR0GZCDBecGEQiLcT7RK7Zz9GhFW8RPNbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}