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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cec44769fbc5f4f73111e4e6b92083710786e32fd0de5f6325ef8b22a2cedc28' 
  AND token = 'RQ5nCvtvZJx6zHCAr8QvNpnLfQqQCL8ll6br8gOVq+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}