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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374d52f288a2722f91a31520caedf0b119e5b1bc14a1aac20c5ca9369140acc0' 
  AND token = 'gLJ0BtLUvag/x9QjSlc1DM7iVtNnFuJ+J6f2fRpgfRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}