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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9253428b85c53f1708350dfa03de892c3544e13e2a197dc09d66048749cd62aa' 
  AND token = '66FCFfpKUI3ttYvJ1cVY294c4ozKs5XBwKds3Fuhg+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}