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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43db0bd8d3ef7229bd270e9de8b17f64f9ab1ff6947e7b14b45facb746d5d402' 
  AND token = 'DG6AFhvxdRc208SPe3S7sMdAatd+6GQRFA3Xjl1mwVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}