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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dfb20f161c410cebc1bd7ad327a843d4e56186736d0b3aa3f05a22552e43765' 
  AND token = 'isE+y+1N/ii4Nmi5Ha+Wo8DQhkKhE4/s34IwC+nWKBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}