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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1641483514b686c5697878c3bf0af018686d8664dd03db24242ed543e4f0617a' 
  AND token = 'RY45ugjOJOap7kweBSvptYX4/K+dX8jTWIyut3/2Xco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}