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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7201b1b6e7be168bcb2b641cd23b94dd7de38530a5724d9ae7e413013f948057' 
  AND token = 'lEySO6auOkT3gUTdFUHTMtFStV6n0kaRdtZeYUSS/NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}