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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451dfdf841ab036b87ef5fbf47172d32af5e4beefae4c65f24bf0f2a2151a21c' 
  AND token = 'pA41ykvJJ/0CBj2NZeK13+t4aYmVs3vHad2mDB3+XXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}