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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6eebb1bc04b12853bcca4eea42395dfedf7443ce42dd23cd19b95bb479ab80f' 
  AND token = 'IUh2moDshed6q1Zd0pyZQsYiGE3fBsdRewqb79ECrJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}