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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '910111f754b926bfee6fe0f331968517e0541f23c20e80008cf85708e4d3e389' 
  AND token = 'bpZx8+Z4mIoZ9b5RoWAQRsuMJIkse3IZpd5iVy3Y5Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}