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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66521c3878ce8a230b2e1ccbca70b7cca002abe3cf21ab6b9439cafb2dead211' 
  AND token = '1/3daRDzyGOQCTpXqKh4Yk3J+zbTBC6N6M+9WsIhiWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}