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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c9c85091e53d96fe13a1aa5d61b80f64ac42e420330477647baa354591c615' 
  AND token = '36kO0uzAFmBXNqqm8urfCxe14lVcHmbT050misr6FoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}