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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a0ae9a69f4074d219bb7c794d21e0915d916f4b9d4d3578b9dade6a5bc0c67' 
  AND token = '42PukIBZIGzazp178WwbyHwAdbT2lSx7oGEjeLOROP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}