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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f8cc748177f6d42f66807f73df0bcf8e8bfb634d51e6dc8365016a6d66ceb18' 
  AND token = '4myK7wmwa756egtIlVTA7MgZAAvsysEOiMBdNVVybp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}