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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a7156c2c6b3f0813e7c605748db9ea336ca09f83724d1fd54e4fac837abe49a' 
  AND token = 'wZTNjkWhx/IexIS+6kOrTRw4+LPoE75rAA5W3Uz49bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}