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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53dfb2c5a3c7f03117719534e9605f0b6aa277acddddfb23f0a4909b38fd56b3' 
  AND token = '46301a18UOAoJ7XGBgjxmO2r+2rH+Km3USGwFg1SPwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}