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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb74db4c2bef1e68007ac9947e260d123780434a814aec5a5154336e71549426' 
  AND token = 'r1NSjaFapdl4OOUcA4UOT7BKVY2yA2R8mStgw5JzrfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}