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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42d2b1f32052855fe2f9059c0204f80032ff3f13a462d00c6e07639ae4f13412' 
  AND token = 'Obmfzkf1E+Eqm8oVj2Y6E2+s4Aj990aZ0CF+yd+LkD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}