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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778d501e4a255abe3d5b8b432eb7c48167e0b08b2a6b9e0ee77b170f750f8d40' 
  AND token = '8ikn0mRLiIMnuEJh2V2yjhlhzCkxlzet4QRffCi59XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}