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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af81f1c1d5a65310fbe56e68eba80c3069ac01af884034888d0343029902e20f' 
  AND token = 'LU44SJmSDwXUWrheCNVaiWxqOfJlaTT0KBS8r/IS4w4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}