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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '573bc41c07dd9049dffd17e12fc6c1f3d33615dc8e81ce6e1034a22dc44c227d' 
  AND token = 'tpS5MsSLvMM30NxY9Cf6cJKm+xEC5VFg7usCcDTtBTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}