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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e0578d3dbe54c0c91ec5c085b4019ad35ce2eaca7179cae1b671dd10dad598' 
  AND token = 'GpOviIl/+B6ZxEis50PLBxErX+98ZSp1MG68EBt8EXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}