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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1605fd73c507b071500a298b79f648c10cb047ada95b49e1e2016ca7107e3c' 
  AND token = 'uc5mVL+6gBuB6aj1+jH929iBhAovytS6KfjccLIjyTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}