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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61e0e6ef860cc32e30479b602ed5efe8d84d642ba714de855fea3db9061d453d' 
  AND token = 'CU4E4rrYi5yMg46KFl+BSwU2F4cDHnRNVK1bF0+5Rf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}