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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543ce148e7cffcae164d791398f58a05d721ebcc57a6d79d7f725713ad6c1ae0' 
  AND token = 'OprnAVOKcYrci/LJE17zJ6rqb1HFYK+grvIms5QKlsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}