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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b974e1aa3bfa22d8ea868fa49d6b0545b176a6b41859fe916030ccb82e9b78' 
  AND token = '9scS9BiEhoiHsGHUu0hSdjNFRamFXtpup4440kgZ0PU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}