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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3404ffdc8c78e2abbfea192d926970cb2fc17d33535a882283aa2bfe80a679b5' 
  AND token = 'TGtPnIDxSkC9Zt41uW6T7/B4tG8Ow+7pthhe+YMWeMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}