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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54120e8b9a864747e86ff8b84f022bc1b44fc63a3cc9d262246df40fd207c30' 
  AND token = 'pY9Pw4xOhCEaW7Y37fmtwjPFwq7AdztKqMqQI1MopPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}