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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b463331b325f30a503b99f0947c9032b8b38ff458d1574b65f9013b7662d308' 
  AND token = 'am82hEdU2nQPjLXrfxWm+D19Rb3cFKLOgVh+rwuamic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}