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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4eed05081d26629c9bc7351c1afc498a01259b4cb3a16c020de788422e1c524' 
  AND token = 'uY77i0PtV3Tk+Qktwk8TbgP1I/imb0vAAbDuZmblBFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}