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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3496780ce572f0620b1afdbc2c8d1a4e6a12193bc0089d821226d7c3be384744' 
  AND token = 'HDZ9zKGJfE4ieE2iuCD1UYLnEEi5czELKquMEDUmvDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}