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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441593444a2664b85ee6d2470bde39eac4febf2f42076ae7cc3683fed1fa017e' 
  AND token = 'JlltsCn+UsHjZdzEBPmgnLd2W8TkqLgYbhEioGZesbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}