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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21bf94dbe0c979fddf40de0fac2476043e61dc6f3045fd35c1065abee6258969' 
  AND token = '01nvKKMH+z1Mu9zOw0ZH2Fwlv89LuxUR4a1MZplsdZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}