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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453d406f453607287ae7e3f1a0b434d2d662b17db3cb0cbd80f3f172f605cdc7' 
  AND token = 'oNceV9nM3qHReGMQhKTrmEN+KdQmQqn1P+xs7dWqu5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}