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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a64500c54b965d507d3c3a839ee123fd5247740317c6558609c4affa0453f647' 
  AND token = 'tozrHNa/ZYtPiCqOdI0zBm7SxGhdiZVayAIbj6k8R2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}