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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e13f520097bedf96a84167fa32059fd03c0573cbb8e1d10e4b2fcd5e7749f8' 
  AND token = 'FM+Pn9I5cdyKqrfCicaVhyMAtggg7Yx6MjtQt67P2DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}