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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d3f698bd60568341d05010b43967f661081781c47ebc572f5de9193e98dd4d' 
  AND token = '4R4JU5E5ZLxk+ldidGJPwDyENwi/pw+9rG3sGvDQAMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}