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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e2c1cfcf85fb627366a60d1e7b95002dcb20de3d2552c4588f3c55f288d8bc' 
  AND token = 'Z4m7Cvs+pvAVr37hqBH36qZBZt8Thso8hZiffHK10mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}