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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9d59cfbed895ef4da530e5c000278fa895ed182b790513b1523b9edbdf206d5' 
  AND token = 'q8NWIJ0JbZH2bfmVmqnLHA1pZZf5B4DPxehaXUA9hFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}