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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f80ad4a713704e358b035d2060bf4a68807f4856d41e27e0250470609b995d7' 
  AND token = 'n6pNJHf/pI7jtXy/8UYHNzIkMJU8cp1DRJAJVWacDVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}