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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1254d77e3274679e4f876fa7c15c3f0f489a304fbc8884450d56a88afcaf67c3' 
  AND token = 'b+U3eaMJQaTIzu36M/pIY5crph694hBmG41KeiLfmsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}