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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e424540401134394ea61f5f17af077ada5c7f45ad155b0c6f4e81424b6faf257' 
  AND token = 'JypRi7EYqE9K5gjjjdjp5XxBkKi2eesRY051uBU1hd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}