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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1dc59e04e962995eb8650d2227f5301b2e826a0f1f74b474aabedac641e601a' 
  AND token = 'jYZGUyERkHeLRkH+gAr2CTzyXgWCpyDUBQtm1ki8U0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}