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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fd244f5561cbfdaf474b55f47f191116b65353a418bbfb335086d2729879a9' 
  AND token = 'YKr1M4O0+hhHV/k3b5Ty+53qHoFgq1Tj59HUUE9pKxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}