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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c981f346ab4cd8ef9c9320644ff40e2f9e4eaa412717dd582936a8186992f7d1' 
  AND token = 'a+rxvkp/07y45asFVmKj8UU02+4PJyZPQnMe/sYPk4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}