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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9b45e3f4700cdd86dfc147c1ea22789460af372b23ffeec127b0cfce70e7af5' 
  AND token = 'bXPyK8/T9VXPNWlLwKYWy36utEudTsyV0SJx8R5o4F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}