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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8c5398eb79c208a16ed49ad29324ea4a3ba0276d350be5ab01887aee05ee8fd' 
  AND token = '0FR5UB2CwCLHn9jfbKeN7s+lbGyE5xBeGAx1sgcUvCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}