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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49505d1ef42eb5187e4aaed132e6af30e3ca5e753c480c83349b15e87c0658fe' 
  AND token = 'CZkNVRc4cvyoUoUbprf5h9Rk2+gPcb/OcSG55jP/n7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}