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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154a4990bec49df187d2043b7fae2e0c726f43643f32427858f558c2d44b2042' 
  AND token = 't+nKQyC4D4baWaM/fjmDSqJWQdKULB7AF0cdAVXi6nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}